skip to primary navigationskip to content
 

Dr Vera Pancaldi

Dr Vera Pancaldi

FEBS Fellow at the Spanish National Cancer Centre, Madrid

CNN Organizer


Research Interests

I am currently a FEBS fellow in the Structural Biology and Biocomputing group at the CNIO (Spanish National Cancer Research Centre) in Madrid, Spain. Until the summer of 2012 I was a post-doc at the Cambridge University Plant Science Department working on RNA silencing in tomato and hybrid vigour in the Baulcombe lab. Before 2010 I worked in Prof. Bähler's lab on fission yeast functional genomics, first at the Welcome Trust Sanger Institute and then at University College London.

You can find my publications here (pdfs available on arXiv if not open access)

 

NEW: 8th July 2016:  Paper on chromatin assortativity out in Genome Biology

What does happiness on twitter have in common with Polycomb proteins binding DNA?

 

Some of the projects I have been working on:

Epigenomics (BLUEPRINT,EpiGeneSys)

Paper on chromatin assortativity (2016)
Paper on chromatin regulators as a guide for cancer treatment choice (2016)

Paper on Expression Variability in CLL (2015)


  • Evolutionary Boolean models of hybrid vigour (paper)
  • Opinion piece on noise in chemotaxis and stress response (paper)
  • Boolean models of cancer networks, embryonal tumours (ASSET project)
  • An online tool for prediction of protein-protein interactions in fission yeast (PInt

  • Effect of stress on yeast interaction networks (paper)
  • Meta-analysis of microarray data for fission yeast in different genetic and environmental conditions
  • Characterisation and prediction of protein-mRNA interactions in budding yeast
  • The role of epigenetic effects and siRNAs in the formation of inter-specific hybrids in tomato
  • Boolean models of stress response in fission yeast

Collaborations:

Peter Fraser, Mikhail Spivakov, the Babraham Institute, Cambridge (3D Chromatin contact maps).

José-Ignacio Martin-Subero, Elias Campo, University of Barcelona (Spanish CLL project).

Branka Radic, Superti-Furga lab at CeMM, Vienna (on cell line models for predicting drug synergies).

Zachary Gurard-Levin, Almouzni Lab at Insitut Curie, Paris (on models for predicting breast cancer drug sensitivities)

Meetings organized:

NetSciReg'15 Network Models in Cellular Regulation, Zaragoza, Spain, 1 June 2015 (a NetSci2015 Satellite)

Modelling Approaches in Epigenetics, 20-21 March 2014, Cambridge, UK

 

 

 

 

Keywords

  • Evolution
  • Biological Networks
  • Cell biology
  • Cancer
  • Functional Genomics
  • Promoter Capture HiC
  • Complex Networks
  • Hybrid vigour
  • Biological noise
  • Chromatin Interaction Networks
  • HiC
  • Complex Systems
  • Complexity
  • Epigenetics
  • Computational Biology
  • Epigenomics
  • Bioinformatics
  • siRNAs Networks
  • Yeast
  • Gene Regulatory Networks